Description

2-Chloro-4-(Difluoromethoxy)Pyridine is a high-value fluorinated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both chloro and difluoromethoxy substituents, makes it an essential intermediate for constructing complex molecules with tailored properties. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key synthon for the development of active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting new therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced crop protection agents, such as herbicides and fungicides, where the difluoromethoxy group can enhance biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for synthesizing specialty chemicals, ligands, or functional materials that require a fluorinated heterocyclic core.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and inhibitors for biochemical and pharmacological studies.

Basic Information

Product Name	2-Chloro-4-(Difluoromethoxy)Pyridine
CAS No.	1206978-15-5
Molecular Formula	C6H4ClF2NO
Molecular Weight	179.55 g/mol
Synonyms	2-Chloro-4-(difluoromethoxy)pyridine; 4-(Difluoromethoxy)-2-chloropyridine; 2-Chloro-4-difluoromethoxypyridine; Pyridine, 2-chloro-4-(difluoromethoxy)-; 1206978-15-5
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Difluoromethoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong bases and sources of fluoride ions. The container must be kept tightly sealed due to potential moisture sensitivity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.