Description

2-Bromo-4-(Trifluoromethoxy)Pyridine is a high-value halogenated pyridine derivative, serving as a critical building block in advanced organic synthesis. Its molecular structure, featuring both bromine and a trifluoromethoxy group, makes it an indispensable intermediate for constructing complex molecules with tailored electronic and steric properties. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethoxy group enhances biological activity and metabolic stability.
• Material Science Research: Serves as a precursor for creating functionalized ligands, organic semiconductors, and liquid crystal materials.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and other palladium-catalyzed cross-coupling reactions to form biaryl structures.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and tags for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A vital starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences sector.

Basic Information

Product Name	2-Bromo-4-(Trifluoromethoxy)Pyridine
CAS No.	1206977-89-0
Molecular Formula	C6H3BrF3NO
Molecular Weight	241.99 g/mol
Synonyms	2-Bromo-4-(trifluoromethoxy)pyridine; 4-(Trifluoromethoxy)-2-bromopyridine; Pyridine, 2-bromo-4-(trifluoromethoxy)-; 2-Bromo-4-trifluoromethoxypyridine
EINECS	Contact for details

Quality Control

Every batch of 2-Bromo-4-(Trifluoromethoxy)Pyridine is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for research and scale-up applications. A Certificate of Analysis (COA) detailing identity, purity (typically by GC/HPLC), and impurity profile is supplied with each shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic (moisture-sensitive) nature, the container should be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Recommended long-term storage temperature is 2-8°C.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥97.0% (Standard Grade)
Purity (HPLC/GC)	≥99.0% (High Purity Grade)
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.