Description

2-Chloro-4-(Trifluoromethoxy)Pyridine is a high-value halogenated pyridine derivative, distinguished by its trifluoromethoxy substituent which imparts unique electronic and steric properties. This compound serves as a critical advanced pharmaceutical intermediate (API) and a versatile building block for the synthesis of complex agrochemicals and specialty materials. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drugs.
• Agrochemical Synthesis: Used as a core building block for novel herbicides, fungicides, and insecticides, leveraging the stability and lipophilicity of the trifluoromethoxy group.
• Ligand and Catalyst Development: Employed in the synthesis of specialized ligands for transition metal catalysis in fine chemical manufacturing.
• Material Science Research: Acts as a precursor for functionalized polymers and liquid crystals due to its aromatic and halogenated structure.
• Custom Synthesis and Contract Manufacturing: Supplied for bespoke organic synthesis projects in academic and industrial research laboratories.

Basic Information

Product Name	2-Chloro-4-(Trifluoromethoxy)Pyridine
CAS No.	1206975-33-8
Molecular Formula	C6H3ClF3NO
Molecular Weight	197.54 g/mol
Synonyms	2-Chloro-4-(trifluoromethoxy)pyridine; 4-(Trifluoromethoxy)-2-chloropyridine; 2-Chloro-4-(trifluoromethoxyl)pyridine; Pyridine, 2-chloro-4-(trifluoromethoxy)-; 1206975-33-8
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(Trifluoromethoxy)Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. The container must be kept tightly closed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.