Description

8-(Chloromethyl)-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyridine is a high-value, heterocyclic organic building block characterized by its fused triazolopyridine core with reactive chloromethyl and isopropyl substituents. This compound is critical for pharmaceutical research and development, serving as a versatile intermediate in the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly in central nervous system (CNS) and anti-infective therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides due to its bioactive heterocyclic structure.
• Chemical Biology Probe: Serves as a scaffold for creating molecular probes to study enzyme function and biological pathways.
• Material Science: Potential precursor for advanced organic electronic materials or metal-organic frameworks (MOFs).
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific synthesis projects.

Basic Information

Product Name	8-(Chloromethyl)-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyridine
CAS No.	1206970-33-3
Molecular Formula	C10H12ClN3
Molecular Weight	209.68 g/mol
Synonyms	3-Isopropyl-8-(chloromethyl)-[1,2,4]triazolo[4,3-a]pyridine; 8-(Chloromethyl)-3-(propan-2-yl)-[1,2,4]triazolo[4,3-a]pyridine; 3-(1-Methylethyl)-8-(chloromethyl)-[1,2,4]triazolo[4,3-a]pyridine; Triazolopyridine Chloromethyl Derivative; CAS 1206970-33-3
EINECS	Contact for details

Quality Control

Every batch of 8-(Chloromethyl)-3-Isopropyl-[1,2,4]Triazolo[4,3-A]Pyridine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.