Description

5-(2-Chloro-5-(Trifluoromethyl)Phenoxy)Pyrazin-2-Amine is a high-purity, advanced pharmaceutical intermediate with the CAS registry number 1206970-21-9. This compound is valued for its role as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring complex heterocyclic scaffolds. It is primarily sought by research institutions and manufacturers in the pharmaceutical and agrochemical industries for developing next-generation small molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of novel drug candidates, especially for targeted therapies.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, leveraging its unique phenoxy-pyrazine structure.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• API Manufacturing: Employed in the scaled-up synthesis of active pharmaceutical ingredients under current Good Manufacturing Practice (cGMP) conditions.
• Material Science: Investigated as a precursor for specialty chemicals and functional materials due to its aromatic and halogenated properties.

Basic Information

Product Name	5-(2-Chloro-5-(Trifluoromethyl)Phenoxy)Pyrazin-2-Amine
CAS No.	1206970-21-9
Molecular Formula	C11H7ClF3N3O
Molecular Weight	289.64 g/mol
Synonyms	5-[(2-Chloro-5-(trifluoromethyl)phenyl)oxy]-2-pyrazinamine; 2-Amino-5-(2-chloro-alpha,alpha,α-trifluoro-p-tolyloxy)pyrazine; 5-(2-Chloro-5-(trifluoromethyl)phenoxy)-2-pyrazinamine; 5-(2-Chloro-5-(trifluoromethyl)phenoxy)pyrazin-2-amine; 2-Pyrazinamine, 5-[(2-chloro-5-(trifluoromethyl)phenyl)oxy]-; 1206970-21-9
EINECS	Contact for details

Quality Control

Our 5-(2-Chloro-5-(Trifluoromethyl)Phenoxy)Pyrazin-2-Amine is manufactured under stringent quality systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and rigorous control of residual solvents and impurities. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.