Description

n-(4-(3-Chloropyrazin-2-Yloxy)Phenyl)Pyridin-2-Amine is a high-purity, advanced pharmaceutical intermediate characterized by its specific heterocyclic structure. This compound matters for its critical role in the synthesis of targeted therapeutic agents, particularly in oncology and other specialized drug development pipelines. It is primarily needed by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in the production of novel active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.
• Oncology Research: Used in the development and scale-up of experimental anti-cancer compounds due to its specific molecular scaffold.
• Chemical Synthesis: Serves as a versatile precursor for further functionalization in medicinal chemistry and process chemistry.
• Biochemical Research: Employed in biochemical assays and as a reference standard for pharmacological studies.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant API production.
• Academic Research: Utilized in university and institutional labs for investigating new synthetic pathways and structure-activity relationships (SAR).

Basic Information

Product Name	n-(4-(3-Chloropyrazin-2-Yloxy)Phenyl)Pyridin-2-Amine
CAS No.	1206970-13-9
Molecular Formula	C15H11ClN4O
Molecular Weight	298.73 g/mol
Synonyms	2-Pyridinamine, N-[4-[(3-chloro-2-pyrazinyl)oxy]phenyl]-; N-(4-((3-Chloropyrazin-2-yl)oxy)phenyl)pyridin-2-amine; 1206970-13-9; N-[4-[(3-Chloropyrazin-2-yl)oxy]phenyl]pyridin-2-amine; 2-Amino-N-(4-(3-chloropyrazin-2-yloxy)phenyl)pyridine; UNII-8J8F2206QN; 8J8F2206QN; BDBM50388859; AKOS025310923; Z57127955
EINECS	Contact for details

Quality Control

Our n-(4-(3-Chloropyrazin-2-Yloxy)Phenyl)Pyridin-2-Amine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and cGMP manufacturing. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled and stored accordingly to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.