Description

1-Acetyl-4-Bromo-1H-Pyrrolo[2,3-B]Pyridin-6-Yl Acetate is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is of significant value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in oncology and kinase inhibitor research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of targeted therapeutic agents, especially kinase inhibitors.
• Oncology Drug Discovery: Serves as a core scaffold for developing novel compounds in cancer research programs.
• Chemical Biology Research: Used as a molecular probe or labeled compound in biochemical and pharmacological studies.
• Process Chemistry & Scale-Up: Employed in route scouting, optimization, and pilot-scale manufacturing of complex molecules.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific API synthesis projects.
• Academic Research: Utilized in university and institutional labs for methodological development and exploring new chemical spaces in medicinal chemistry.

Basic Information

Product Name	1-Acetyl-4-Bromo-1H-Pyrrolo[2,3-B]Pyridin-6-Yl Acetate
CAS No.	1206679-09-5
Molecular Formula	C11H9BrN2O3
Molecular Weight	297.11 g/mol
Synonyms	4-Bromo-1-acetyl-1H-pyrrolo[2,3-b]pyridin-6-yl acetate; 6-Acetoxy-4-bromo-1-acetyl-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-6-ol, 4-bromo-1-acetyl-, acetate (ester); 1206679-09-5; 4-Bromo-1-acetyl-6-acetoxy-1H-pyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Our 1-Acetyl-4-Bromo-1H-Pyrrolo[2,3-B]Pyridin-6-Yl Acetate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting batch-specific results.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.