Description

8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine is a high-value, heterocyclic organic compound featuring a fused triazolopyridine core with halogen and trifluoromethyl substituents. This specific molecular architecture makes it a critical advanced pharmaceutical intermediate (API) and a versatile building block for medicinal chemistry research. It is primarily sought after by R&D and process development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly in oncology, CNS, and anti-infective therapeutic areas.
• Agrochemical Research: Used as a building block for developing new herbicides, fungicides, and insecticides, leveraging the biological activity of the triazole and pyridine motifs.
• Medicinal Chemistry & SAR Studies: Employed in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for investigating biological pathways and target validation.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced polymers and electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine
CAS No.	1206640-61-0
Molecular Formula	C7H4ClF3N4
Molecular Weight	236.58 g/mol
Synonyms	8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine; 8-Chloro-6-(trifluoromethyl)-1,2,4-triazolo[1,5-a]pyridin-2-amine; 2-Amino-8-chloro-6-(trifluoromethyl)[1,2,4]triazolo[1,5-a]pyridine; 1206640-61-0; [1,2,4]Triazolo[1,5-a]pyridin-2-amine, 8-chloro-6-(trifluoromethyl)-; 8-Chloro-6-trifluoromethyl-[1,2,4]triazolo[1,5-a]pyridin-2-ylamine
EINECS	Contact for details

Quality Control

Our production of 8-Chloro-6-(trifluoromethyl)-[1,2,4]triazolo[1,5-a]pyridin-2-amine adheres to stringent internal quality standards to ensure batch-to-batch consistency and high purity, suitable for research and development applications. Each batch is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and MS. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive; containers should be opaque or stored in darkness.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.