Description

2-Bromo-4-nitro-6-chloropyridine is a halogenated and nitrated pyridine derivative, a versatile and high-value synthetic intermediate. Its unique substitution pattern makes it a critical building block for constructing complex molecular architectures in advanced chemical synthesis. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drug candidates targeting various therapeutic areas.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive halogen and nitro groups for further functionalization.
• Material Science Research: Serves as a building block for creating functionalized ligands, organic semiconductors, and other specialty polymers.
• Chemical Biology Probes: Employed in the design and synthesis of molecular probes and tags for studying biological systems.
• Cross-Coupling Reactions: An excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) to form complex biaryl structures.
• Nucleophilic Aromatic Substitution: The chlorine and bromine atoms are susceptible to displacement by various nucleophiles, enabling diverse chemical modifications.

Basic Information

Product Name	2-Bromo-4-nitro-6-chloropyridine
CAS No.	1206250-42-1
Molecular Formula	C5H2BrClN2O2
Molecular Weight	237.44 g/mol
Synonyms	6-Chloro-2-bromo-4-nitropyridine; 2-Bromo-6-chloro-4-nitropyridine; 4-Nitro-2-bromo-6-chloropyridine; Pyridine, 2-bromo-4-nitro-6-chloro-; 2-Br-4-NO2-6-Cl-Pyridine
EINECS	Contact for details

Quality Control

Our 2-Bromo-4-nitro-6-chloropyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which can affect product stability and performance.

Specification

Item	Specification
Appearance	White to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.