Description

2-Bromo-3-Chloropyrazine is a high-purity halogenated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its unique bifunctional halogenation pattern makes it an exceptionally versatile intermediate for constructing complex heterocyclic systems. This compound is primarily sought after by research and development chemists in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging the pyrazine core for bioactivity.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of novel organic electronic materials and ligands for catalysis.
• Cross-Coupling Reactions: An excellent substrate for Suzuki, Stille, and Buchwald-Hartwig amination reactions due to the reactive bromo and chloro substituents.
• Chemical Library Development: Employed in combinatorial and parallel synthesis for high-throughput screening and drug discovery programs.

Basic Information

Product Name	2-Bromo-3-Chloropyrazine
CAS No.	1206250-01-2
Molecular Formula	C4H2BrClN2
Molecular Weight	193.43 g/mol
Synonyms	3-Chloro-2-bromopyrazine; 2-Bromo-3-chloro-1,4-diazine; Pyrazine, 2-bromo-3-chloro-; Bromochloropyrazine
EINECS	Contact for details

Quality Control

Our 2-Bromo-3-Chloropyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.