Description

tert-Butyl (5-Chloropyrazin-2-Yl)Carbamate is a high-purity, specialized chemical building block of significant importance in advanced organic synthesis. This compound serves as a critical protected intermediate for the development of novel active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by research and development teams, process chemists, and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to construct complex heterocyclic molecules with precision.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of drug candidates, particularly those containing pyrazine cores for therapeutic areas like oncology and central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the chloropyrazine moiety can impart specific biological activity.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and the creation of novel chemical libraries for screening.
• Fine Chemical Production: Serves as a precursor for other high-value, functionalized pyrazine derivatives used in various specialty chemical applications.
• Peptide Mimetics & Conjugate Chemistry: The carbamate protecting group makes it valuable for constructing peptide-like structures or conjugating the pyrazine unit to other molecular scaffolds.

Basic Information

Product Name	tert-Butyl (5-Chloropyrazin-2-Yl)Carbamate
CAS No.	1206249-43-5
Molecular Formula	C9H12ClN3O2
Molecular Weight	229.66 g/mol
Synonyms	5-Chloro-2-[(tert-butoxycarbonyl)amino]pyrazine; 2-((tert-Butoxycarbonyl)amino)-5-chloropyrazine; tert-Butyl N-(5-chloropyrazin-2-yl)carbamate; Boc-5-chloro-2-aminopyrazine; (5-Chloro-pyrazin-2-yl)-carbamic acid tert-butyl ester; 2-Amino-5-chloropyrazine, N-Boc protected; N-Boc-5-chloro-2-aminopyrazine; N-(tert-Butoxycarbonyl)-5-chloro-2-aminopyrazine
EINECS	Contact for details

Quality Control

Our tert-Butyl (5-Chloropyrazin-2-Yl)Carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to guarantee traceability and batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.