Description

2-(2-Chloropyridin-4-Yl)Ethanol CAS NO 1206247-86-0 is a high-purity pyridine derivative serving as a crucial chiral building block and pharmaceutical intermediate. Its molecular structure, featuring both a chloropyridine moiety and an ethanol side chain, makes it a versatile synthon for constructing complex molecules in medicinal chemistry. This compound is primarily utilized by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for the development of active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and anti-infective agents.
• Agrochemical Synthesis: Building block for developing novel herbicides, insecticides, and fungicides, leveraging the bioactivity of the chloropyridine structure.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and asymmetric synthesis.
• Material Science Research: Intermediate for creating functionalized polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Serves as a starting point for synthesizing molecular probes and tags used in biochemical assay development.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects at various scales.

Basic Information

Product Name	2-(2-Chloropyridin-4-Yl)Ethanol
CAS No.	1206247-86-0
Molecular Formula	C7H8ClNO
Molecular Weight	157.60 g/mol
Synonyms	4-(2-Hydroxyethyl)-2-chloropyridine; 2-Chloro-4-(2-hydroxyethyl)pyridine; 2-(2-Chloro-4-pyridinyl)ethanol; 2-Chloropyridin-4-ylethanol; (2-Chloropyridin-4-yl)ethanol; 2-(2-Chloro-4-pyridyl)ethanol; 2-Chloro-4-pyridineethanol
EINECS	Contact for details

Quality Control

Every batch of 2-(2-Chloropyridin-4-Yl)Ethanol is manufactured under a strict quality management system and undergoes comprehensive analytical testing. We ensure compliance with relevant industry standards for fine chemicals and pharmaceutical intermediates. A detailed Certificate of Analysis (COA), confirming identity, purity, and impurity profiles via techniques such as HPLC, GC, NMR, and IR spectroscopy, is provided with each shipment to guarantee supply reliability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.