Description

tert-Butyl 4-(3-Chloro-3-oxopropyl)piperazine-1-carboxylate is a versatile and high-purity chemical building block, specifically a piperazine derivative, used in advanced organic synthesis. This compound is valued for its role as a key intermediate in the development of active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new pesticides and herbicides, leveraging its reactive chloro and carbonyl groups.
• Organic Synthesis Reagent: Serves as a protected piperazine precursor for introducing the piperazine moiety into more complex molecules in medicinal chemistry.
• Chemical Research & Development: Employed in academic and industrial R&D labs for method development and exploring new chemical entities.
• Fine Chemical Production: Integral in the multi-step synthesis of specialty chemicals requiring high-purity intermediates.

Basic Information

Product Name	tert-Butyl 4-(3-Chloro-3-oxopropyl)piperazine-1-carboxylate
CAS No.	1206185-14-9
Molecular Formula	C12H21ClN2O3
Molecular Weight	276.76 g/mol
Synonyms	1-Boc-4-(3-chloropropionyl)piperazine; tert-Butyl 4-(3-chloropropanoyl)piperazine-1-carboxylate; 4-(3-Chloro-3-oxopropyl)piperazine-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-4-(3-chloropropionyl)piperazine; 3-Chloro-1-(1-piperazinyl)-1-propanone 1-Boc derivative; Boc-piperazine-4-(3-chloropropionyl); Piperazine, 4-(3-chloro-1-oxopropyl)-, 1-(1,1-dimethylethyl) ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(3-Chloro-3-oxopropyl)piperazine-1-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. Keep away from strong acids and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.