Description

Glpg-0778 is a high-purity, non-peptidic small molecule compound of significant interest in pharmaceutical research and development. This compound serves as a critical intermediate or active pharmaceutical ingredient (API) for investigating novel therapeutic pathways. It is primarily utilized by research institutions and pharmaceutical companies engaged in drug discovery and preclinical studies. Our supply ensures consistent quality and reliable availability for critical R&D workflows.

Application

• Pharmaceutical Research & Development: Key intermediate in the synthesis of novel drug candidates for various disease targets.
• Biochemical Assay Development: Used as a reference standard or tool compound in high-throughput screening and mechanism-of-action studies.
• Preclinical Studies: Employed in in vitro and in vivo models to evaluate pharmacokinetics, efficacy, and safety profiles.
• Chemical Biology: Serves as a probe to study specific protein functions and signaling pathways within cells.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and the production of larger batches under GMP or non-GMP conditions.
• Contract Research Organizations (CROs): Essential material for outsourced drug discovery and testing services.

Basic Information

Product Name	Glpg-0778
CAS No.	1206163-45-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	GLPG0778; GLPG-0778; UNII-9V8P23U4QJ; 9V8P23U4QJ; 1206163-45-2; (4S)-4-[[4-[[3-(2,6-Dichlorophenyl)-5-isopropyl-1,2,4-triazol-1-yl]methyl]pyridin-2-yl]oxy]piperidine-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our Glpg-0778 is manufactured and tested under strict quality management systems. Each batch undergoes comprehensive analytical characterization to ensure identity, purity, and consistency. Standard testing includes HPLC for assay and related substances, residual solvent analysis, and confirmation of structure. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting compliance with agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.