Description

(4R,12As)-7-(Benzyloxy)-9-Bromo-4-Methyl-3,4-Dihydro-2H-[1,3]Oxazino[3,2-D]Pyrido[1,2-A]Pyrazine-6,8(12H,12Ah)-Dione is a high-purity, advanced pharmaceutical intermediate characterized by its complex heterocyclic structure. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular architectures. It is primarily utilized by pharmaceutical R&D organizations and contract manufacturing organizations (CMOs) engaged in the development of new chemical entities.

Application

This specialized intermediate serves as a key precursor in advanced organic synthesis. Its primary applications include:

• Pharmaceutical Research & Development: As a crucial building block for synthesizing novel drug candidates, particularly in complex molecule libraries.
• Active Pharmaceutical Ingredient (API) Synthesis: Used in multi-step synthetic routes for the production of target APIs in preclinical and clinical development stages.
• Medicinal Chemistry: Enabling structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry Development: Serving as a standard or intermediate for scaling up and optimizing synthetic pathways in pilot plants.
• Contract Research & Manufacturing: Supplied to CROs and CMOs specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Item	Details
Product Name	(4R,12As)-7-(Benzyloxy)-9-Bromo-4-Methyl-3,4-Dihydro-2H-[1,3]Oxazino[3,2-D]Pyrido[1,2-A]Pyrazine-6,8(12H,12Ah)-Dione
CAS No.	1206102-10-4
Molecular Formula	C22H19BrN2O4
Molecular Weight	455.30 g/mol
Synonyms	9-Bromo-7-(benzyloxy)-4-methyl-3,4,12,12a-tetrahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8-dione; (4R,12aR)-7-(Benzyloxy)-9-bromo-4-methyl-3,4,12,12a-tetrahydro-2H-[1,3]oxazino[3,2-d]pyrido[1,2-a]pyrazine-6,8-dione; 1206102-10-4; CAS 1206102-10-4; Advanced Pharmaceutical Intermediate; Bromo-oxazino-pyrido-pyrazine-dione derivative
EINECS	Contact for details

Quality Control

Our (4R,12As)-7-(Benzyloxy)-9-Bromo-4-Methyl-3,4-Dihydro-2H-[1,3]Oxazino[3,2-D]Pyrido[1,2-A]Pyrazine-6,8(12H,12Ah)-Dione is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications and test results are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept tightly sealed in a dry environment to maintain product integrity over time.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Single Unknown Impurity	≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.