Description

3-((4-Nitrophenethylamino)Methyl)Piperidine-1-Carboxylic Tert Butyl Ester is a high-purity, advanced pharmaceutical intermediate featuring a piperidine scaffold with a protected amine and a nitrophenethyl moiety. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers focused on developing new therapeutic agents, particularly in areas such as central nervous system (CNS) and oncology drug discovery.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of potential drug candidates, especially those targeting neurological receptors.
• Medicinal Chemistry Research: Used as a scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Protecting Group Chemistry: The tert-butyloxycarbonyl (Boc) group allows for selective deprotection during complex synthetic sequences.
• Ligand Synthesis: Employed in the development of novel ligands for G-protein-coupled receptors (GPCRs) and other biological targets.
• Chemical Biology Probes: Useful for creating tagged molecules to study biological pathways and protein interactions.
• Custom Synthesis: Serves as a starting material for contract research organizations (CROs) and CDMOs producing bespoke compounds for client projects.

Basic Information

Product Name	3-((4-Nitrophenethylamino)Methyl)Piperidine-1-Carboxylic Tert Butyl Ester
CAS No.	1204812-31-6
Molecular Formula	C19H29N3O4
Molecular Weight	363.46 g/mol
Synonyms	1-Boc-3-((4-nitrophenethylamino)methyl)piperidine; tert-Butyl 3-(((4-nitrophenethyl)amino)methyl)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-3-((4-nitrophenethylamino)methyl)piperidine; 3-[(2-(4-Nitrophenyl)ethylamino)methyl]piperidine-1-carboxylic acid tert-butyl ester; 3-((4-Nitrophenethylamino)Methyl)Piperidine-1-Carboxylic Acid 1,1-Dimethylethyl Ester; 1204812-31-6; 1-Boc-3-((4-nitrophenethylamino)methyl)piperidine
EINECS	Contact for details

Quality Control

Our 3-((4-Nitrophenethylamino)Methyl)Piperidine-1-Carboxylic Tert Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.