Description

3-(4-Nitrophenethylamino)Piperidine-1-Carboxylic Acid Tert Butyl Ester is a high-purity, advanced pharmaceutical intermediate characterized by its piperidine core and protected carboxylic acid group. This compound is of significant value in medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries for creating potential drug candidates targeting central nervous system and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules and novel chemical entities.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Process Chemistry Development: Employed in scaling up synthetic routes from laboratory to pilot plant and commercial manufacturing scales.
• Building Block for API Synthesis: Integral for constructing piperidine-containing pharmacophores found in various therapeutic agents.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for the production of specialized compounds.
• Academic & Institutional Research: Used in university and research institute laboratories for chemical biology and synthetic methodology studies.

Basic Information

Item	Details
Product Name	3-(4-Nitrophenethylamino)Piperidine-1-Carboxylic Acid Tert Butyl Ester
CAS No.	1204811-03-9
Molecular Formula	C18H27N3O4
Molecular Weight	349.43 g/mol
Synonyms	1-Boc-3-[(2-(4-nitrophenyl)ethyl)amino]piperidine; tert-Butyl 3-[(2-(4-nitrophenyl)ethyl)amino]piperidine-1-carboxylate; 3-[(2-(4-Nitrophenyl)ethyl)amino]-1-piperidinecarboxylic Acid 1,1-Dimethylethyl Ester; 1,1-Dimethylethyl 3-[[2-(4-nitrophenyl)ethyl]amino]-1-piperidinecarboxylate; 3-(4-Nitrophenethylamino)Piperidine-1-Carboxylic Acid 1,1-Dimethylethyl Ester; 1-Boc-3-(4-nitrophenethylamino)piperidine; Boc-3-(4-nitrophenethylamino)piperidine
EINECS	Contact for details

Quality Control

Our 3-(4-Nitrophenethylamino)Piperidine-1-Carboxylic Acid Tert Butyl Ester is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); the container must be kept tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/IR)	Conforms to reference standard
Assay (HPLC)	≥ 97.0%
Purity (HPLC, Area %)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.