Description

Pyrrolo[1,2-A]Pyrazine, Octahydro-, Hydrochloride (1:1), (8Ar)- is a high-purity, specialized heterocyclic building block and pharmaceutical intermediate. Its value lies in its complex, saturated pyrrolopyrazine core, which is a privileged scaffold in medicinal chemistry for the development of novel bioactive compounds. This product is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly those focused on synthesizing new drug candidates, chemical probes, and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of potential active pharmaceutical ingredients (APIs), especially in central nervous system (CNS) and antiviral research.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its three-dimensional, nitrogen-rich heterocyclic structure.
• Agrochemical Development: Serves as a precursor in the research and synthesis of novel herbicides, fungicides, or insecticides with new modes of action.
• Chemical Biology & Probe Development: Utilized to create chemical probes for studying biological pathways and target validation in early-stage drug discovery.
• Fine Chemical Synthesis: Employed in custom synthesis and contract manufacturing for producing complex, high-value specialty chemicals.
• Academic Research: Used in university and institutional labs for methodological development in organic synthesis and heterocyclic chemistry.

Basic Information

Item	Details
Product Name	Pyrrolo[1,2-A]Pyrazine, Octahydro-, Hydrochloride (1:1), (8Ar)-
CAS No.	1204603-41-7
Molecular Formula	C7H15ClN2
Molecular Weight	162.66 g/mol
Synonyms	(8aR)-Octahydropyrrolo[1,2-a]pyrazine hydrochloride; (R)-Octahydro-1H-pyrrolo[1,2-a]pyrazine hydrochloride; (R)-Hexahydro-1H,1'H-[2,3']bipyrrolizinyl hydrochloride; (8aR)-1,2,3,5,6,7,8,8a-Octahydropyrrolo[1,2-a]pyrazine hydrochloride; Pyrrolo[1,2-a]pyrazine, octahydro-, hydrochloride (1:1), (8aR)-; (R)-Octahydropyrrolo[1,2-a]pyrazine HCl
EINECS	Contact for details

Quality Control

Every batch of Pyrrolo[1,2-A]Pyrazine, Octahydro-, Hydrochloride (1:1), (8Ar)- is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency, supporting your regulatory and research needs. A detailed Certificate of Analysis (COA) is supplied with each shipment, typically including results for assay (HPLC), chiral purity, residual solvents, and related substances.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.