Description

1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Formyl-, Methyl Ester is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters as a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug molecules, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for novel therapeutic targets.
• API Development: Serves as a core scaffold for constructing active pharmaceutical ingredients in oncology and anti-inflammatory research pipelines.
• Chemical Biology Probes: Utilized in the development of molecular probes to study enzyme function and cellular signaling pathways.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and process development for the pharmaceutical industry.

Basic Information

Item	Detail
Product Name	1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Formyl-, Methyl Ester
CAS No.	1204475-76-2
Molecular Formula	C10H8N2O3
Molecular Weight	204.18 g/mol
Synonyms	Methyl 3-formyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylate; 1H-Pyrrolo[2,3-b]pyridine-2-carboxylic acid, 3-formyl-, methyl ester; 3-Formyl-1H-pyrrolo[2,3-b]pyridine-2-carboxylic acid methyl ester; Methyl 3-formyl-7-azaindole-2-carboxylate; 3-Formyl-7-azaindole-2-carboxylic acid methyl ester; 1204475-76-2; CAS 1204475-76-2
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine-2-Carboxylic Acid, 3-Formyl-, Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.