Description

6-(2,4-Difluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a distinct difluorophenyl-substituted dihydropyridone core structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with enhanced metabolic stability and bioavailability. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly in areas such as kinase inhibitors and other small-molecule drugs.

Application

• Pharmaceutical Intermediate: A key synthon in the research and commercial synthesis of novel drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs to explore new chemical entities.
• API Synthesis: Serves as a crucial precursor in the multi-step manufacturing process of complex target molecules.
• Biochemical Tool Compound: May be utilized in biochemical assays and as a reference standard for analytical method development.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic Research: Employed in university and institutional labs for exploratory organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	6-(2,4-Difluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylic Acid
CAS No.	1204296-90-1
Molecular Formula	C12H7F2NO3
Molecular Weight	251.19 g/mol
Synonyms	2-Oxo-6-(2,4-difluorophenyl)-1,2-dihydropyridine-3-carboxylic acid; 6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydro-3-pyridinecarboxylic acid; 3-Pyridinecarboxylic acid, 1,2-dihydro-6-(2,4-difluorophenyl)-2-oxo-; 1204296-90-1; 6-(2,4-Difluorophenyl)-2-oxo-1,2-dihydropyridine-3-carboxylate
EINECS	Contact for details

Quality Control

Our 6-(2,4-Difluorophenyl)-2-Oxo-1,2-Dihydropyridine-3-Carboxylic Acid is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for full traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.