Description

2-Chloro-4-(1,1-Difluoroethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate characterized by its unique halogenated pyridine structure. This compound matters as a critical building block in modern organic synthesis, enabling the development of novel active ingredients with enhanced properties. It is primarily needed by research and development teams in the agrochemical and pharmaceutical industries for creating new crop protection agents and therapeutic molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders.
• Agrochemical Research: Serves as a versatile precursor for developing next-generation herbicides and insecticides, leveraging the biological activity of the difluoroethyl and chloropyridine motifs.
• Ligand & Catalyst Development: Used in organometallic chemistry to create specialized ligands for catalysis, benefiting from the pyridine nitrogen's coordinating ability.
• Material Science Research: Employed in the synthesis of functionalized polymers and advanced organic materials requiring specific halogenated aromatic components.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects and scale-up processes in fine chemical production.

Basic Information

Product Name	2-Chloro-4-(1,1-Difluoroethyl)Pyridine
CAS No.	1204295-63-5
Molecular Formula	C7H6ClF2N
Molecular Weight	177.58 g/mol
Synonyms	2-Chloro-4-(1,1-difluoroethyl)pyridine; 4-(1,1-Difluoroethyl)-2-chloropyridine; Pyridine, 2-chloro-4-(1,1-difluoroethyl)-; 2-Chloro-4-(α,α-difluoroethyl)pyridine
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-(1,1-Difluoroethyl)Pyridine is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistent identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.