Description

3-(Trifluoromethylthio)Pyridin-2-Amine is a high-value, multi-functional pyridine derivative distinguished by its trifluoromethylthio substituent. This compound is a critical synthetic intermediate prized for its ability to impart unique physicochemical properties, such as enhanced lipophilicity and metabolic stability, into target molecules. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the development of new drug candidates, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders, anti-infectives, and oncology.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides, where the trifluoromethylthio group can improve biological activity and environmental profile.
• Material Science Research: Serves as a precursor for functionalized ligands and monomers in the development of specialty polymers and advanced materials.
• Chemical Biology: Employed as a probe or tagging reagent in biochemical research due to its distinctive fluorine signature for detection (e.g., 19F NMR).
• Custom Synthesis & Contract Manufacturing: A vital starting material for fine chemical manufacturers offering bespoke synthesis services to the life science industry.

Basic Information

Product Name	3-(Trifluoromethylthio)Pyridin-2-Amine
CAS No.	1204234-81-0
Molecular Formula	C6H5F3N2S
Molecular Weight	194.18 g/mol
Synonyms	2-Amino-3-(trifluoromethylthio)pyridine; 3-((Trifluoromethyl)thio)pyridin-2-amine; 2-Pyridinamine, 3-[(trifluoromethyl)thio]-; 3-(Trifluoromethylsulfanyl)pyridin-2-amine; 3-(Trifluoromethylthio)-2-aminopyridine; 3-(Trifluoromethylthio)-2-pyridinamine
EINECS	Contact for details

Quality Control

Every batch of 3-(Trifluoromethylthio)Pyridin-2-Amine is manufactured under strict quality management systems. Our products undergo rigorous analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.