Description

2-Aminopyridin-3-Ylboronic Acid CAS NO 1204112-62-8 is a high-value boronic acid derivative, a key building block in modern synthetic chemistry. Its primary value lies in its dual functionality, enabling efficient cross-coupling reactions like the Suzuki-Miyaura reaction to construct complex heterocyclic scaffolds. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: A crucial building block for synthesizing active pharmaceutical ingredients (APIs), particularly in the development of kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and production of novel herbicides, fungicides, and insecticides with improved efficacy and selectivity.
• Material Science Research: Serves as a precursor for creating organic electronic materials, such as those used in OLEDs and sensors, due to its functionalized pyridine core.
• Chemical Biology & Proteomics: Employed in the synthesis of molecular probes and bioconjugates for studying biological pathways and protein interactions.
• Cross-Coupling Reactions: Primarily utilized in palladium-catalyzed Suzuki-Miyaura couplings to form carbon-carbon bonds, enabling the construction of complex, functionalized biphenyl and heterobiaryl structures.
• Ligand Synthesis: Acts as a starting material for the preparation of bidentate and tridentate ligands used in catalysis and coordination chemistry.

Basic Information

Product Name	2-Aminopyridin-3-Ylboronic Acid
CAS No.	1204112-62-8
Molecular Formula	C5H7BN2O2
Molecular Weight	137.94 g/mol
Synonyms	(3-Amino-2-pyridinyl)boronic acid; 2-Amino-3-pyridineboronic acid; 3-Amino-2-pyridineboronic acid; 2-Amino-3-pyridinylboronic acid; Boronic acid, B-(3-amino-2-pyridinyl)-; 2-Amino-3-pyridylboronic acid; 2-Aminopyridine-3-boronic acid; 1204112-62-8
EINECS	Contact for details

Quality Control

Our 2-Aminopyridin-3-Ylboronic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and commercial synthesis. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to maintain stability and purity. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥97.0%
Water Content (KF)	≤1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.