Description

tert-Butyl 3-(2-Bromophenyl)Pyrrolidine-1-Carboxylate is a high-value, protected pyrrolidine derivative that serves as a critical building block in modern synthetic chemistry. Its molecular architecture, featuring a brominated aromatic ring and a Boc-protected amine, makes it an indispensable intermediate for the construction of complex nitrogen-containing heterocycles. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients and advanced materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of drug candidates targeting central nervous system (CNS) disorders, oncology, and inflammation.
• Agrochemical Synthesis: Building block for creating novel pesticides, herbicides, and fungicides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Research: Employed in the design and synthesis of molecular probes and bio-conjugates for studying biological pathways.
• Material Science: Intermediate for the production of specialty polymers and advanced organic electronic materials.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs for the scalable production of bespoke chemical entities under cGMP conditions.

Basic Information

Item	Details
Product Name	tert-Butyl 3-(2-Bromophenyl)Pyrrolidine-1-Carboxylate
CAS No.	1203685-04-4
Molecular Formula	C15H20BrNO2
Molecular Weight	326.23 g/mol
Synonyms	1-Boc-3-(2-bromophenyl)pyrrolidine; tert-Butyl 3-(2-bromophenyl)-1-pyrrolidinecarboxylate; 3-(2-Bromophenyl)-1-(tert-butoxycarbonyl)pyrrolidine; 1-(tert-Butoxycarbonyl)-3-(2-bromophenyl)pyrrolidine; 3-(2-Bromophenyl)pyrrolidine-1-carboxylic acid tert-butyl ester; BOC-3-(2-Bromophenyl)pyrrolidine; 1203685-04-4; 3-(2-Bromophenyl)-N-Boc-pyrrolidine
EINECS	Contact for details

Quality Control

Our production of tert-Butyl 3-(2-Bromophenyl)Pyrrolidine-1-Carboxylate adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity. Each lot is fully characterized and tested against rigorous in-house specifications, which are aligned with ICH guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity (typically >97% by HPLC), and impurity profiles is provided with every shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 97.0%
Related Substances (HPLC)	Any single impurity ≤ 1.0%; Total impurities ≤ 3.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.