Description

5-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-4-Ol is a high-value fluorinated heterocyclic building block, a key intermediate in modern pharmaceutical and agrochemical research. Its core value lies in its unique pyrrolopyridine scaffold, which is instrumental in modulating the biological activity and pharmacokinetic properties of target molecules. This compound is primarily needed by R&D chemists and process development scientists in the pharmaceutical industry for the synthesis of novel drug candidates, particularly kinase inhibitors and other targeted therapies.

Application

• Pharmaceutical Intermediate: A critical building block for the synthesis of active pharmaceutical ingredients (APIs), especially in the development of kinase inhibitors for oncology and inflammatory diseases.
• Agrochemical Research: Used in the discovery and development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Chemical Biology & Medicinal Chemistry: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Material Science Precursor: Potential use in the synthesis of advanced organic materials, such as ligands for catalysts or components in organic electronics, due to its electron-rich nitrogen heterocycle.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations specializing in custom synthesis and scale-up services for the life sciences sector.

Basic Information

Product Name	5-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-4-Ol
CAS No.	1203499-60-8
Molecular Formula	C7H5FN2O
Molecular Weight	152.13 g/mol
Synonyms	4-Hydroxy-5-fluoro-1H-pyrrolo[2,3-b]pyridine; 5-Fluoro-4-hydroxy-1H-pyrrolo[2,3-b]pyridine; 1H-Pyrrolo[2,3-b]pyridin-4-ol, 5-fluoro-; 5-Fluoro-1H-pyrrolo[2,3-b]pyridin-4-ol; 5-Fluoro-4-hydroxypyrrolo[2,3-b]pyridine; 1203499-60-8; 5-F-1H-Pyrrolo[2,3-B]Pyridin-4-Ol
EINECS	Contact for details

Quality Control

Our 5-Fluoro-1H-Pyrrolo[2,3-B]Pyridin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided to guarantee traceability, consistency, and compliance with your project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.