Description

n-(6-((3-((tert-Butyldimethylsilyloxy)Methyl)Pyrrolidin-1-Yl)Methyl)-2-Chloropyridin-3-Yl)Pivalamid is a sophisticated, high-purity chemical intermediate featuring a unique molecular architecture combining a protected pyrrolidine moiety with a chloropyridine core. This compound matters for its critical role as a key building block in the synthesis of complex active pharmaceutical ingredients (APIs), where its specific functional groups enable precise molecular modifications. Pharmaceutical R&D and process chemistry teams need this intermediate to develop and scale up novel therapeutic candidates, particularly in targeted drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a crucial building block in the multi-step synthesis of novel drug candidates, particularly in medicinal chemistry.
• API Synthesis: Used in the research, development, and scale-up production of Active Pharmaceutical Ingredients (APIs) for various therapeutic areas.
• Process Chemistry: Employed in route scouting and optimization for the efficient, scalable manufacturing of complex organic molecules.
• Chemical Biology Research: Utilized as a probe or precursor in the study of biological pathways and target validation.
• Custom Synthesis: A starting material for contract research and manufacturing organizations (CROs/CMOs) producing specialized compounds for clients.
• Agrochemical Research: Potential application as an intermediate in the development of new crop protection agents with specific modes of action.

Basic Information

Item	Detail
Product Name	n-(6-((3-((tert-Butyldimethylsilyloxy)Methyl)Pyrrolidin-1-Yl)Methyl)-2-Chloropyridin-3-Yl)Pivalamid
CAS No.	1203499-53-9
Molecular Formula	C22H38ClN3O2Si
Molecular Weight	440.10 g/mol
Synonyms	Pivalamid, N-[6-[[3-[[(1,1-Dimethylethyl)dimethylsilyl]oxy]methyl]-1-pyrrolidinyl]methyl]-2-chloro-3-pyridinyl]-; 1203499-53-9; tert-Butyl((1-((6-(pivalamido)-5-chloropyridin-2-yl)methyl)pyrrolidin-3-yl)methoxy)dimethylsilane; N-(6-((3-((tert-Butyldimethylsilyloxy)methyl)pyrrolidin-1-yl)methyl)-2-chloropyridin-3-yl)pivalamide; 2-Chloro-N-(6-(((3-((((tert-butyldimethylsilyl)oxy)methyl)pyrrolidin-1-yl)methyl)pyridin-3-yl)pivalamide
EINECS	Contact for details

Quality Control

Our n-(6-((3-((tert-Butyldimethylsilyloxy)Methyl)Pyrrolidin-1-Yl)Methyl)-2-Chloropyridin-3-Yl)Pivalamid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and structural identity suitable for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, impurities, and other critical parameters are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This compound is light-sensitive and should be stored away from light. Keep the container tightly sealed to protect from moisture and incompatible materials such as fluorides and strong alkalis.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Total Impurities	≤ 3.0%
Residual Solvents (GC)	Meets ICH guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.