Description

n-(2-Bromo-5-Iodopyridin-3-Yl)Pivalamide is a high-purity, multi-halogenated pyridine derivative designed for advanced synthetic chemistry. This compound serves as a critical versatile building block for constructing complex molecular architectures in pharmaceutical and agrochemical research. It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries to introduce halogenated pyridine motifs into target molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the halogenated pyridine core for bioactivity.
• Cross-Coupling Reactions: Serves as an excellent substrate for palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Stille, Sonogashira) due to the presence of both bromo and iodo substituents, allowing for selective functionalization.
• Ligand and Material Precursor: Employed in the development of specialized ligands for catalysis and as a building block for organic electronic materials.
• Chemical Biology Probes: Utilized in medicinal chemistry to create molecular probes for target identification and validation studies.

Basic Information

Product Name	n-(2-Bromo-5-Iodopyridin-3-Yl)Pivalamide
CAS No.	1203498-93-4
Molecular Formula	C10H12BrIN2O
Molecular Weight	381.03 g/mol
Synonyms	2-Bromo-5-iodo-3-pivalamidopyridine; Pivalamide, N-(2-bromo-5-iodo-3-pyridinyl)-; 3-Pyridinecarboxamide, 2-bromo-5-iodo-N-(1,1-dimethylethyl)-; N-(2-Bromo-5-iodopyridin-3-yl)-2,2-dimethylpropanamide; N-tert-Butyl-2-bromo-5-iodonicotinamide
EINECS	Contact for details

Quality Control

Our n-(2-Bromo-5-Iodopyridin-3-Yl)Pivalamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.