Description

3-Benzylamino-Piperidine-1-Carboxylic Acid tert-Butyl Ester-Hcl CAS NO 1203127-48-3 is a high-purity, protected piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its role as a versatile chiral intermediate, enabling the construction of complex molecular architectures with high stereochemical control. This compound is essential for research and development chemists in the pharmaceutical and agrochemical industries, particularly for the synthesis of active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: Key chiral building block for the synthesis of central nervous system (CNS) active drugs, receptor antagonists, and enzyme inhibitors.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its piperidine scaffold.
• Chemical Biology & Proteomics: Serves as a precursor for designing molecular probes, enzyme substrates, and activity-based protein profiling (ABPP) reagents.
• Peptidomimetics & Drug Discovery: Integral for creating constrained peptide analogs and non-peptide scaffolds in medicinal chemistry programs.
• Catalyst & Ligand Development: Used to synthesize novel chiral ligands for asymmetric catalysis and metal complexes.
• Academic & Contract Research: A valuable reagent for methodological development in organic synthesis and heterocyclic chemistry at research institutions and CROs.

Basic Information

Product Name	3-Benzylamino-Piperidine-1-Carboxylic Acid tert-Butyl Ester-Hcl
CAS No.	1203127-48-3
Molecular Formula	C18H29ClN2O2
Molecular Weight	340.89 g/mol
Synonyms	3-(Benzylamino)piperidine-1-carboxylic acid tert-butyl ester hydrochloride; tert-Butyl 3-(benzylamino)piperidine-1-carboxylate hydrochloride; 1-Boc-3-(benzylamino)piperidine hydrochloride; 3-Benzylamino-1-N-Boc-piperidine HCl; 1-(tert-Butoxycarbonyl)-3-(benzylamino)piperidine hydrochloride; N-Benzyl-1-N-Boc-3-aminopiperidine hydrochloride; 3-(Phenylmethylamino)-1-piperidinecarboxylic acid 1,1-dimethylethyl ester hydrochloride
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is characterized using advanced analytical techniques to guarantee identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, impurities, and other critical parameters are available upon request. We adhere to strict quality management protocols suitable for research and development applications in regulated industries.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.