Description

6-Chloro-3-Methylpicolinonitrile is a high-purity, versatile heterocyclic building block of significant interest in advanced organic synthesis. Its molecular structure, featuring both a chloro and a nitrile substituent on the pyridine ring, makes it a critical intermediate for constructing complex molecules. This compound is primarily utilized by research and development chemists in the pharmaceutical and agrochemical industries. Its reliable quality and consistent performance are essential for streamlining the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of active pharmaceutical ingredients (APIs), particularly in kinase inhibitor and other small-molecule drug discovery programs.
• Agrochemical Synthesis: Serves as a core building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Ligand and Catalyst Development: Used in the preparation of specialized ligands for metal-catalyzed cross-coupling reactions and other catalytic processes.
• Material Science Research: Employed in the synthesis of functionalized polymers, liquid crystals, and organic electronic materials.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity intermediates.

Basic Information

Product Name	6-Chloro-3-Methylpicolinonitrile
CAS No.	1201924-31-3
Molecular Formula	C7H5ClN2
Molecular Weight	152.58 g/mol
Synonyms	6-Chloro-3-methylpyridine-2-carbonitrile; 3-Methyl-6-chloropicolinonitrile; 2-Cyano-6-chloro-3-methylpyridine; 6-Chloro-3-methyl-2-pyridinecarbonitrile; 6-Chloro-3-picolinonitrile
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-Methylpicolinonitrile is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality parameters. Our quality commitment supports compliance with cGMP and ICH guidelines for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed when not in use to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.