Description

6-Chloro-2-(4-tert-Butoxycarbonylpiperazino)-4-(Trifluoromethyl)Pyridine is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethylpyridine core. This compound matters for its critical role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular modifications. Pharmaceutical R&D teams and fine chemical manufacturers need it to develop next-generation drugs, leveraging its piperazine and halogenated pyridine structure to create potent and selective candidates.

Application

• Pharmaceutical Intermediate: A key building block for the research and development of new drug candidates, especially in oncology and central nervous system (CNS) disorders.
• Kinase Inhibitor Synthesis: Used in constructing potent and selective kinase inhibitors, a major class of targeted cancer therapies.
• Agrochemical Research: Serves as a precursor in developing novel pesticides and herbicides, where the trifluoromethyl group enhances biological activity and stability.
• Chemical Biology Probes: Employed in the design of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring complex heterocyclic chemistry.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and advanced organic materials.

Basic Information

Product Name	6-Chloro-2-(4-tert-Butoxycarbonylpiperazino)-4-(Trifluoromethyl)Pyridine
CAS No.	1201675-03-7
Molecular Formula	C15H18ClF3N3O2
Molecular Weight	364.77 g/mol
Synonyms	2-(4-(tert-Butoxycarbonyl)piperazin-1-yl)-6-chloro-4-(trifluoromethyl)pyridine; 6-Chloro-2-(4-Boc-piperazinyl)-4-trifluoromethylpyridine; 1-Boc-4-(6-chloro-4-(trifluoromethyl)pyridin-2-yl)piperazine; tert-Butyl 4-(6-chloro-4-(trifluoromethyl)pyridin-2-yl)piperazine-1-carboxylate; 1201675-03-7; Boc-Piperazine-Pyridine Derivative
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for pharmaceutical intermediates. Every batch is analyzed using advanced techniques like HPLC and NMR to confirm identity, purity, and the absence of critical impurities. Certificates of Analysis (COA) are available upon request, providing full transparency and traceability for your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.