Description

(R)-Methyl 4-(3-Methylpiperazin-1-yl)benzoate is a high-purity chiral intermediate of significant importance in advanced pharmaceutical synthesis. Its core value lies in its role as a key building block for the development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring high stereoselectivity. This compound is essential for research and manufacturing organizations in the pharmaceutical, biotechnology, and fine chemical sectors focused on innovative drug discovery and process development.

Application

• Pharmaceutical Intermediate: A critical chiral building block for the synthesis of novel, enantiomerically pure drug candidates and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Used in the development of catalytic asymmetric reactions and chiral ligand synthesis due to its defined stereochemistry.
• Medicinal Chemistry Research: Serves as a versatile scaffold in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• Process Chemistry & Scale-up: Employed in the development and optimization of scalable, robust synthetic routes for commercial pharmaceutical manufacturing.
• Reference Standard: Utilized as a high-purity analytical standard for method development, validation, and quality control in regulatory submissions.

Basic Information

Product Name	(R)-Methyl 4-(3-Methylpiperazin-1-yl)benzoate
CAS No.	1201670-92-9
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	Methyl (R)-4-(3-methylpiperazin-1-yl)benzoate; (R)-Methyl 4-(3-methyl-1-piperazinyl)benzoate; Benzoic acid, 4-(3-methyl-1-piperazinyl)-, methyl ester, (R)-; Methyl 4-[(3R)-3-methylpiperazin-1-yl]benzoate; (R)-4-(3-Methylpiperazin-1-yl)benzoic acid methyl ester; (R)-MMPB; (R)-Methyl 4-(3-Methylpiperazinyl)benzoate
EINECS	Contact for details

Quality Control

Our (R)-Methyl 4-(3-Methylpiperazin-1-yl)benzoate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis by HPLC, to ensure it meets the stringent requirements for pharmaceutical R&D and production. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, identity, and purity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.