Description

(R)-Methyl 4-(3,4-Dimethylpiperazin-1-Yl)Benzoate is a high-purity chiral intermediate of significant importance in modern pharmaceutical synthesis. Its value lies in its role as a key building block for the development of novel, optically active active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and pharmaceutical companies engaged in the discovery and process development of new therapeutic agents, particularly in areas requiring specific stereochemistry.

Application

• Pharmaceutical Intermediate: A critical chiral building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Asymmetric Synthesis: Used in the development of catalytic and stoichiometric asymmetric synthesis routes for complex molecules.
• Process Chemistry & Scale-Up: Serves as a defined starting material for optimizing and scaling up API manufacturing processes under GMP conditions.
• Medicinal Chemistry Research: Enables structure-activity relationship (SAR) studies by providing a versatile, enantiomerically pure piperazine-containing scaffold.
• Reference Standard: Can be utilized as a high-purity analytical standard for method development and quality control in pharmaceutical analysis.
• Custom Synthesis: Acts as a precursor for the custom synthesis of more complex, proprietary compounds for client-specific R&D projects.

Basic Information

Item	Detail
Product Name	(R)-Methyl 4-(3,4-Dimethylpiperazin-1-Yl)Benzoate
CAS No.	1201670-91-8
Molecular Formula	C14H20N2O2
Molecular Weight	248.32 g/mol
Synonyms	Methyl (R)-4-(3,4-dimethylpiperazin-1-yl)benzoate; (R)-Methyl 4-(3,4-dimethyl-1-piperazinyl)benzoate; Benzoic acid, 4-(3,4-dimethyl-1-piperazinyl)-, methyl ester, (R)-; (R)-4-(3,4-Dimethylpiperazin-1-yl)benzoic acid methyl ester; Methyl (R)-4-(3,4-dimethylpiperazino)benzoate; (R)-enantiomer of Methyl 4-(3,4-dimethylpiperazin-1-yl)benzoate
EINECS	Contact for details

Quality Control

Our (R)-Methyl 4-(3,4-Dimethylpiperazin-1-Yl)Benzoate is produced under strict quality management systems to ensure batch-to-batch consistency and high enantiomeric purity. All materials are subjected to rigorous analytical testing, including chiral HPLC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, chiral purity, and impurity profiles is provided with each shipment to support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) in a desiccator for long-term storage to prevent moisture uptake. Recommended storage temperature is 2-8°C for prolonged stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.