Description

5-Tosyl-5H-Pyrrolo[2,3-B]Pyrazine-2-Carboxylic Acid is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound is a critical building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for targeted therapies. It is essential for research and development chemists in the pharmaceutical, biotechnology, and fine chemical industries working on innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, especially kinase inhibitors and other targeted cancer therapeutics.
• Organic Synthesis Building Block: Used in medicinal chemistry for constructing fused pyrrolopyrazine scaffolds, which are privileged structures in drug design.
• Research & Development: Serves as a standard or starting material in academic and industrial R&D labs for exploring new chemical entities and biological pathways.
• Process Chemistry: Employed in the scale-up and optimization of synthetic routes for potential new drug candidates during clinical development phases.

Basic Information

Product Name	5-Tosyl-5H-Pyrrolo[2,3-B]Pyrazine-2-Carboxylic Acid
CAS No.	1201630-75-2
Molecular Formula	C16H13N3O4S
Molecular Weight	343.36 g/mol
Synonyms	5H-Pyrrolo[2,3-b]pyrazine-2-carboxylic acid, 5-[(4-methylphenyl)sulfonyl]-; 5-(Tosyl)-5H-pyrrolo[2,3-b]pyrazine-2-carboxylic acid; 5-(4-Methylbenzenesulfonyl)-5H-pyrrolo[2,3-b]pyrazine-2-carboxylic acid; 5-Tosyl-5H-pyrrolo[2,3-b]pyrazine-2-carboxylic acid; CAS 1201630-75-2; Pyrrolopyrazine-2-carboxylic acid tosyl derivative
EINECS	Contact for details

Quality Control

Our production of 5-Tosyl-5H-Pyrrolo[2,3-B]Pyrazine-2-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting cGMP and ISO standards for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container sealed to protect from moisture and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.