Description

6-Chloro-3-Phenyl-1,5-Naphthyridin-2(1H)-One is a high-purity, advanced pharmaceutical intermediate belonging to the naphthyridine class of heterocyclic compounds. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel drug candidates with targeted biological activity. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and anti-infective research.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex active pharmaceutical ingredients (APIs) for preclinical and clinical research.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies to optimize potency and selectivity of drug molecules.
• Kinase Inhibitor Development: Serves as a building block for potential kinase inhibitors, a major class of targeted cancer therapies.
• Chemical Biology Probes: Utilized in the creation of molecular probes to study specific biological pathways and protein functions.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and process development services.
• Academic Research: Employed in university and institutional labs for novel heterocyclic chemistry and drug discovery projects.

Basic Information

Product Name	6-Chloro-3-Phenyl-1,5-Naphthyridin-2(1H)-One
CAS No.	1199556-78-9
Molecular Formula	C₁₄H₉ClN₂O
Molecular Weight	256.69 g/mol
Synonyms	6-Chloro-3-phenyl-1,5-naphthyridin-2(1H)-one; 6-Chloro-3-phenyl-1,5-naphthyridin-2-ol; 2(1H)-Naphthyridinone, 6-chloro-3-phenyl-; 6-Chloro-3-phenyl-1H-1,5-naphthyridin-2-one; 6-Chloro-3-phenyl-1,5-dihydronaphthyridin-2-one; 1199556-78-9 (CAS); 6-Cl-3-Ph-1,5-Naphthyridinone
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and pharmaceutical development. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for purity, residual solvents, and related substances are available upon request. We adhere to strict internal quality management protocols to ensure supply reliability and batch-to-batch reproducibility.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.