Description

9-Bromo-Pyrido[1,2-A]Pyrimidin-4-One is a high-value brominated heterocyclic building block used in advanced organic synthesis. This compound is critical for medicinal chemistry research and pharmaceutical development, serving as a versatile precursor for creating novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates targeting various therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its reactive bromine site.
• Agrochemical Synthesis: Intermediate in the development of new pesticides and herbicides.
• Material Science: Potential precursor for organic electronic materials and ligands in catalysis.
• Cross-Coupling Reactions: Serves as a substrate in Suzuki, Buchwald-Hartwig, and other palladium-catalyzed cross-coupling reactions.
• Library Synthesis: Used in parallel and combinatorial chemistry to generate diverse compound libraries for high-throughput screening.

Basic Information

Product Name	9-Bromo-Pyrido[1,2-A]Pyrimidin-4-One
CAS No.	1198413-08-9
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	9-Bromopyrido[1,2-a]pyrimidin-4-one; 9-Bromo-4H-pyrido[1,2-a]pyrimidin-4-one; 9-Bromo-4-oxo-4H-pyrido[1,2-a]pyrimidine; 1198413-08-9; 9-Bromo-4H-pyrido[1,2-a]pyrimidin-4-one; 9-Bromopyrido[1,2-a]pyrimidin-4(1H)-one; 9-Bromo-1H-pyrido[1,2-a]pyrimidin-4-one
EINECS	Contact for details

Quality Control

Our 9-Bromo-Pyrido[1,2-A]Pyrimidin-4-One is manufactured under strict quality control protocols to ensure high purity and batch-to-batch consistency, suitable for demanding research and development applications. We provide comprehensive Certificates of Analysis (COA) with each batch, detailing purity, identity, and impurity profiles as determined by advanced analytical techniques. Our quality management system supports compliance with cGMP and ISO standards for reliable sourcing.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep the container sealed to protect from moisture. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.