Description

2-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)Piperazine is a high-purity, advanced pharmaceutical intermediate and versatile heterocyclic building block. Its unique fused dioxin-piperazine structure makes it a critical synthon for the development of novel active pharmaceutical ingredients (APIs) and fine chemicals. This compound is essential for research and production in pharmaceutical chemistry, agrochemical development, and advanced material science, where precise molecular architecture is required.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of central nervous system (CNS) active drugs, potential antipsychotics, and serotonin receptor modulators.
• Agrochemical Research: Used in the development of novel herbicides and pesticides, leveraging its heterocyclic scaffold for bioactivity.
• Organic Synthesis & Catalysis: Serves as a versatile ligand or precursor in catalytic systems and complex organic molecule construction.
• Material Science: Investigated as a monomer or functional unit for creating specialized polymers and organic electronic materials.
• Academic & R&D: A valuable compound for medicinal chemistry research, structure-activity relationship (SAR) studies, and library synthesis in drug discovery.

Basic Information

Product Name	2-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)Piperazine
CAS No.	1198355-99-5
Molecular Formula	C12H16N2O2
Molecular Weight	220.27 g/mol
Synonyms	6-(Piperazin-1-yl)-2,3-dihydro-1,4-benzodioxine; 1-(2,3-Dihydro-1,4-benzodioxin-6-yl)piperazine; 2,3-Dihydro-1,4-benzodioxin-6-yl-piperazine; 2,3-Dihydrobenzo[1,4]dioxin-6-ylpiperazine; 6-Piperazinyl-2,3-dihydro-1,4-benzodioxine; 2-(2,3-Dihydro-1,4-benzodioxin-6-yl)piperazine
EINECS	Contact for details

Quality Control

Our 2-(2,3-Dihydrobenzo[B][1,4]Dioxin-6-Yl)Piperazine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing all specifications and test results. We support cGMP and ISO standards for pharmaceutical and research-grade intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.