Description

1-Boc-4-(1-Naphthalenyl)-4-Piperidinecarboxylic Acid is a high-purity, advanced pharmaceutical intermediate featuring a protected piperidine core. This compound is critical for medicinal chemistry research and development, serving as a versatile building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical and biotechnology industries to create new therapeutic candidates.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules, particularly those targeting the central nervous system (CNS) and other therapeutic areas.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities with improved efficacy and safety profiles.
• Process Chemistry Development: Serves as a starting material or intermediate in scaling up synthetic routes from laboratory to pilot plant and commercial production.
• Protease Inhibitor Synthesis: The piperidinecarboxylic acid structure is valuable in constructing inhibitors for various enzymatic targets.
• Chemical Library Production: Employed in combinatorial chemistry and high-throughput screening to generate diverse compound libraries for biological testing.
• Academic Research: Used in university and institutional labs for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	1-Boc-4-(1-Naphthalenyl)-4-Piperidinecarboxylic Acid
CAS No.	1198287-04-5
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	1-Boc-4-(1-Naphthyl)-4-piperidinecarboxylic Acid; 4-(Naphthalen-1-yl)-1-(tert-butoxycarbonyl)piperidine-4-carboxylic Acid; tert-Butyl 4-(1-naphthyl)-4-(carboxy)piperidine-1-carboxylate; 1-(tert-Butoxycarbonyl)-4-(1-naphthyl)piperidine-4-carboxylic Acid; 4-(1-Naphthyl)-1-Boc-piperidine-4-carboxylic Acid; N-Boc-4-(1-naphthyl)isonipecotic Acid; 1-Boc-4-(1-Naphthalenyl)piperidine-4-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 1-Boc-4-(1-Naphthalenyl)-4-Piperidinecarboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with full analytical data are provided for every shipment, supporting compliance with cGMP and ICH guidelines for pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to prevent degradation. For long-term storage, consider storing under an inert atmosphere such as argon or nitrogen.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.