Description

n-(4-Benzylpiperazin-1-Yl)-2,2,2-Trifluoro-Acetamide is a specialized trifluoroacetamide derivative featuring a benzylpiperazine moiety, offering a unique combination of structural motifs valuable for advanced chemical synthesis. This compound matters as a high-purity building block for research and development, enabling the creation of novel molecules with potential biological activity. It is primarily needed by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers focused on developing new active ingredients and complex intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders or requiring fluorinated pharmacophores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trifluoromethyl group can enhance metabolic stability and bioavailability.
• Chemical Biology Probe: Acts as a precursor for creating molecular probes to study enzyme inhibition or receptor-ligand interactions in biochemical assays.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis to introduce the N-(benzylpiperazinyl)trifluoroacetamide functional group into more complex molecular architectures.
• Material Science Research: Potential monomer or precursor for specialty polymers and advanced materials where fluorine incorporation is desired for specific properties.

Basic Information

Product Name	n-(4-Benzylpiperazin-1-Yl)-2,2,2-Trifluoro-Acetamide
CAS No.	1198285-47-0
Molecular Formula	C13H16F3N3O
Molecular Weight	287.28 g/mol
Synonyms	N-(4-Benzylpiperazin-1-yl)-2,2,2-trifluoroacetamide; 2,2,2-Trifluoro-N-[4-(phenylmethyl)-1-piperazinyl]acetamide; 1-Benzyl-4-(2,2,2-trifluoroacetamido)piperazine; 4-Benzyl-1-(2,2,2-trifluoroacetyl)piperazine; TFA-Benzylpiperazine; BPTFA
EINECS	Contact for details

Quality Control

Our n-(4-Benzylpiperazin-1-Yl)-2,2,2-Trifluoro-Acetamide is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles where applicable for pharmaceutical-grade material.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.