Description

tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-2-Yl)Piperidine-1-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a complex heterocyclic structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block in the synthesis of targeted small molecule therapeutics. It is primarily sought after by pharmaceutical companies, biotechnology firms, and contract research organizations (CROs) engaged in the discovery of novel kinase inhibitors and other biologically active compounds.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of novel drug candidates, particularly in oncology and immunology research.
• Kinase Inhibitor Synthesis: Used as a core scaffold for constructing potent and selective kinase inhibitors, leveraging its fused pyrrolopyridine-piperidine motif.
• Medicinal Chemistry Research: Employed in structure-activity relationship (SAR) studies and lead optimization programs to improve drug-like properties.
• Bioconjugation & Probe Development: The tert-butyloxycarbonyl (Boc) protecting group allows for selective deprotection, enabling its use in creating labeled probes or conjugate molecules for biological studies.
• Contract Manufacturing (CMO): Supplied to contract manufacturing organizations for use in the cGMP production of active pharmaceutical ingredients (APIs) for clinical trials.
• Academic Research: Utilized in university and institutional labs for fundamental research in organic synthesis and chemical biology.

Basic Information

Product Name	tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-2-Yl)Piperidine-1-Carboxylate
CAS No.	1198283-79-2
Molecular Formula	C17H23N3O2
Molecular Weight	301.39 g/mol
Synonyms	1-Boc-4-(1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine; 1-(tert-Butoxycarbonyl)-4-(1H-pyrrolo[2,3-b]pyridin-2-yl)piperidine; 4-(1H-Pyrrolo[2,3-b]pyridin-2-yl)piperidine-1-carboxylic acid tert-butyl ester; tert-Butyl 4-(1H-7-azaindol-2-yl)piperidine-1-carboxylate; 2-(1-Boc-4-piperidyl)-1H-pyrrolo[2,3-b]pyridine; BOC-4-(1H-Pyrrolo[2,3-B]Pyridin-2-Yl)Piperidine; 1198283-79-2
EINECS	Contact for details

Quality Control

Our tert-Butyl 4-(1H-Pyrrolo[2,3-B]Pyridin-2-Yl)Piperidine-1-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, supporting its use in regulated research and development environments.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container should be kept tightly sealed in a desiccated environment to prevent moisture absorption, which may affect stability and handling.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.