Description

6-Methyl-1H,2H,3H-Pyrido[2,3-B][1,4]Oxazin-2-One is a high-purity heterocyclic organic compound with the CAS number 1198153-91-1, serving as a critical advanced pharmaceutical intermediate (API) and a versatile building block in medicinal chemistry. Its fused pyrido-oxazinone core structure makes it a valuable scaffold for synthesizing novel bioactive molecules, particularly in drug discovery programs targeting the central nervous system and other therapeutic areas. This compound is essential for research institutions, CROs, and pharmaceutical manufacturers engaged in the development of new chemical entities and fine chemical synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used as a core scaffold in structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.
• Organic Synthesis: Serves as a versatile precursor for constructing complex heterocyclic systems through various chemical transformations.
• Contract Research & Development (CRO/CDMO): Supplied to research organizations for custom synthesis and process development projects.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and developing new synthetic methodologies.
• Agrochemical Intermediate: Potential application in the research and development of new active ingredients for crop protection.

Basic Information

Item	Details
Product Name	6-Methyl-1H,2H,3H-Pyrido[2,3-B][1,4]Oxazin-2-One
CAS No.	1198153-91-1
Molecular Formula	C8H8N2O2
Molecular Weight	164.16 g/mol
Synonyms	6-Methyl-1H,2H,3H-pyrido[2,3-b][1,4]oxazin-2-one; 6-Methyl-2H,3H-pyrido[2,3-b][1,4]oxazin-2-one; 6-Methyl-3,4-dihydro-1H-pyrido[2,3-b][1,4]oxazin-2-one; Pyrido[2,3-b][1,4]oxazin-2-one, 6-methyl-1H,2H,3H-; 1198153-91-1; 6-Methyl-1,2,3,4-tetrahydropyrido[2,3-b][1,4]oxazin-2-one
EINECS	Contact for details

Quality Control

Our 6-Methyl-1H,2H,3H-Pyrido[2,3-B][1,4]Oxazin-2-One is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including HPLC, NMR, and MS, to confirm identity and purity. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing all specifications and test results. We support cGMP standards for pharmaceutical applications and can provide regulatory starting material documentation upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.