Description

1-(Piperidine-4-Carbonyl)Piperazine Dihydrochloride is a high-purity, versatile chemical building block with significant value in advanced organic synthesis. Its bifunctional piperidine-piperazine core structure makes it a critical intermediate for constructing complex molecules with targeted biological activity. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and other fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in central nervous system (CNS) and oncology research.
• Chemical Research & Development: Used as a versatile scaffold for creating libraries of compounds in medicinal chemistry and high-throughput screening.
• Ligand Synthesis: Employed in the preparation of complex ligands for catalysis and metal-organic frameworks (MOFs).
• Peptidomimetic Chemistry: Serves as a constrained dipeptide surrogate to modulate the properties of peptide-based therapeutics.
• Agrochemical Research: Investigated as an intermediate for developing new crop protection agents and pesticides.

Basic Information

Product Name	1-(Piperidine-4-Carbonyl)Piperazine Dihydrochloride
CAS No.	1197831-75-6
Molecular Formula	C11H22Cl2N3O
Molecular Weight	283.22 g/mol
Synonyms	1-(Piperidine-4-carbonyl)piperazine dihydrochloride; 1-(4-Piperidylcarbonyl)piperazine dihydrochloride; 4-(Piperazine-1-carbonyl)piperidine dihydrochloride; Piperazine, 1-(4-piperidinylcarbonyl)-, dihydrochloride; 1-(Piperidine-4-Carbonyl)Piperazine 2HCl
EINECS	Contact for details

Quality Control

Our 1-(Piperidine-4-Carbonyl)Piperazine Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.