Description

3-(Trifluoromethyl)Pyrazine-2-Carbaldehyde is a high-value fluorinated pyrazine derivative, serving as a critical building block in advanced organic synthesis. Its unique structure, featuring both a reactive aldehyde group and a stable trifluoromethyl substituent, makes it indispensable for creating novel compounds with tailored properties. This intermediate is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the development of new active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, oncology, and anti-infectives.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where the trifluoromethyl group can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in catalysis and material science applications.
• Fluorinated Compound Library: Essential for constructing diverse fluorinated compound libraries for high-throughput screening in drug discovery.
• Advanced Material Research: Investigated as a monomer or precursor for specialty polymers and electronic materials requiring specific fluorination.

Basic Information

Product Name	3-(Trifluoromethyl)Pyrazine-2-Carbaldehyde
CAS No.	1197238-20-2
Molecular Formula	C6H3F3N2O
Molecular Weight	176.10 g/mol
Synonyms	2-Pyrazinecarboxaldehyde, 3-(trifluoromethyl)-; 3-(Trifluoromethyl)-2-pyrazinecarbaldehyde; 3-Trifluoromethylpyrazine-2-carboxaldehyde; 3-Trifluoromethyl-2-pyrazinecarboxaldehyde; (3-Trifluoromethylpyrazin-2-yl)methanal; 2-Formyl-3-(trifluoromethyl)pyrazine
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Pyrazine-2-Carbaldehyde is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and scale-up applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). This compound is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.