Description

6-Fluoro-Pyrazine-2-Carboxylic Acid is a high-purity fluorinated heterocyclic building block essential for advanced organic synthesis. This compound is valued for its role in introducing both a fluorine atom and a carboxylic acid functional group into complex molecular architectures, enabling precise modulation of physicochemical properties. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for the creation of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting kinase inhibitors and other biologically active molecules.
• Agrochemical Synthesis: Used in the design and synthesis of advanced herbicides, fungicides, and insecticides, where the fluorine atom can enhance metabolic stability and bioavailability.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands in coordination chemistry and catalysis, useful in asymmetric synthesis.
• Material Science Research: Employed in the synthesis of functionalized heterocyclic compounds for organic electronic materials and advanced polymers.
• Chemical Biology Probes: Utilized as a building block for developing fluorescent tags or molecular probes to study biological systems.
• Custom Synthesis and Contract Manufacturing: A critical starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) serving the life sciences industry.

Basic Information

Item	Detail
Product Name	6-Fluoro-Pyrazine-2-Carboxylic Acid
CAS No.	1197231-27-8
Molecular Formula	C5H3FN2O2
Molecular Weight	142.09 g/mol
Synonyms	6-Fluoropyrazine-2-carboxylic acid; 2-Fluoro-6-pyrazinecarboxylic acid; 6-Fluoro-2-pyrazinecarboxylic acid; 6-Fluoropyrazinecarboxylic acid; 2-Pyrazinecarboxylic acid, 6-fluoro-; 6-Fluoropyrazine-2-carboxylate; 6-Fluoro-2-carboxypyrazine
EINECS	Contact for details

Quality Control

Every batch of 6-Fluoro-Pyrazine-2-Carboxylic Acid is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to guarantee it meets the stringent requirements for research and commercial synthesis.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.