Description

4-Chloro-2-Piperazinobenzoic Acid is a high-value, synthetically versatile organic building block characterized by its benzoic acid core substituted with a piperazine ring and a chlorine atom. This unique structure makes it a critical intermediate for the research and development of novel pharmaceutical compounds, particularly in medicinal chemistry. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing complex molecules with potential biological activity.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of active pharmaceutical ingredients (APIs), especially for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used as a scaffold or building block for constructing compound libraries in drug discovery programs to explore structure-activity relationships (SAR).
• Agrochemical Synthesis: Employed in the development of novel herbicides, fungicides, or insecticides due to its heterocyclic structure.
• Fine Chemical Production: Acts as an intermediate for the manufacture of specialty chemicals, dyes, and complex organic materials.
• Bioconjugation & Probe Development: The carboxylic acid and piperazine functional groups allow for derivatization to create biochemical probes or labeling agents.

Basic Information

Product Name	4-Chloro-2-Piperazinobenzoic Acid
CAS No.	1197193-35-3
Molecular Formula	C11H13ClN2O2
Molecular Weight	240.69 g/mol
Synonyms	2-(Piperazin-1-yl)-4-chlorobenzoic Acid; 4-Chloro-2-(1-piperazinyl)benzoic Acid; 4-Chloro-2-piperazin-1-ylbenzoic Acid; Benzoic acid, 4-chloro-2-(1-piperazinyl)-; 4-Chloro-2-piperazinobenzoic acid; 1197193-35-3; 4-Chloro-2-(piperazin-1-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Piperazinobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.