Description

4-Bromo-2-Piperazinobenzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its brominated benzoic acid core linked to a piperazine moiety. This compound matters for its critical role as a versatile building block in the synthesis of complex, biologically active molecules, particularly in medicinal chemistry. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new drug candidates, especially those targeting central nervous system (CNS) disorders and other therapeutic areas requiring sophisticated heterocyclic scaffolds.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and drug candidates.
• Medicinal Chemistry Research: Used extensively in structure-activity relationship (SAR) studies and lead optimization for discovering new therapeutics.
• CNS Drug Development: A valuable scaffold for creating compounds targeting neurological and psychiatric conditions.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and target validation.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for bespoke chemical synthesis projects.
• Academic Research: Used in university and institutional labs for fundamental organic synthesis and heterocyclic chemistry studies.

Basic Information

Product Name	4-Bromo-2-Piperazinobenzoic Acid
CAS No.	1197193-25-1
Molecular Formula	C11H13BrN2O2
Molecular Weight	285.14 g/mol
Synonyms	4-Bromo-2-(piperazin-1-yl)benzoic acid; 2-(Piperazin-1-yl)-4-bromobenzoic acid; Benzoic acid, 4-bromo-2-(1-piperazinyl)-; 4-Bromo-2-piperazin-1-ylbenzoic acid; 4-Bromo-2-(1-piperazinyl)benzoic acid; 1197193-25-1; 4-Bromo-2-piperazinobenzoic acid
EINECS	Contact for details

Quality Control

Our 4-Bromo-2-Piperazinobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.