Description

3-(4-Methyl-1-Piperazinyl)-4-(Methylsulfonyl)Benzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzoic acid core functionalized with methylpiperazinyl and methylsulfonyl groups. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in the development of new therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the multi-step synthesis of potential drug candidates, especially in oncology and central nervous system (CNS) therapeutic areas.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize the potency and selectivity of lead compounds.
• API Development: Integral in the process development and scale-up stages for new active pharmaceutical ingredients requiring this specific chemical scaffold.
• Biochemical Tool Compound: May be employed in biochemical assays to study enzyme inhibition or receptor binding mechanisms.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) specializing in custom synthesis for client-specific molecular entities.

Basic Information

Product Name	3-(4-Methyl-1-Piperazinyl)-4-(Methylsulfonyl)Benzoic Acid
CAS No.	1197193-05-7
Molecular Formula	C13H18N2O4S
Molecular Weight	298.36 g/mol
Synonyms	4-(Methylsulfonyl)-3-(4-methylpiperazin-1-yl)benzoic acid; 3-(4-Methylpiperazin-1-yl)-4-(methylsulfonyl)benzoic acid; Benzoic acid, 3-(4-methyl-1-piperazinyl)-4-(methylsulfonyl)-; 1197193-05-7; 4-Methylsulfonyl-3-(4-methylpiperazin-1-yl)benzoic acid
EINECS	Contact for details

Quality Control

Our 3-(4-Methyl-1-Piperazinyl)-4-(Methylsulfonyl)Benzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.