Description

4-(Methylsulfonyl)-3-Piperazinobenzoic Acid is a high-purity, advanced pharmaceutical intermediate characterized by its distinct benzoic acid core substituted with piperazine and methylsulfonyl functional groups. This compound is of significant commercial importance for its role in the synthesis of novel, biologically active molecules, particularly in medicinal chemistry. It is primarily utilized by research institutions and pharmaceutical development companies engaged in the creation of new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key building block in the research and synthesis of new drug candidates, especially those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization processes due to its versatile chemical scaffold.
• Protease Inhibitor Development: Serves as a precursor or core structure in the development of enzyme inhibitors, given the potential reactivity of its functional groups.
• Chemical Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs performing bespoke synthesis for client projects.

Basic Information

Product Name	4-(Methylsulfonyl)-3-Piperazinobenzoic Acid
CAS No.	1197193-03-5
Molecular Formula	C12H16N2O4S
Molecular Weight	284.33 g/mol
Synonyms	3-Piperazino-4-(methylsulfonyl)benzoic acid; Benzoic acid, 4-(methylsulfonyl)-3-piperazino-; 4-Methanesulfonyl-3-piperazin-1-yl-benzoic acid; 4-(Methylsulfonyl)-3-(piperazin-1-yl)benzoic acid; 1197193-03-5; 4-Methylsulfonyl-3-piperazinobenzoic acid
EINECS	Contact for details

Quality Control

Our 4-(Methylsulfonyl)-3-Piperazinobenzoic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR, MS), to ensure it meets the high standards required for pharmaceutical research. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The product may be hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.