Description

1H-Pyrrolo[2,3-B]Pyridin-3-Amine, 4,5-Difluoro- is a high-purity, fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because its unique pyrrolopyridine core, functionalized with amine and fluorine groups, provides a versatile scaffold for constructing complex molecules with tailored properties. It is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for drug discovery and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other small-molecule therapeutics targeting various disease pathways.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, where the fluorine atoms can enhance bioavailability and environmental stability.
• Chemical Biology Probe: Employed as a building block for creating fluorescent tags, molecular probes, and other tools for studying biological systems.
• Material Science: Acts as a monomer or functional additive in the research of advanced polymers and organic electronic materials.
• Custom Synthesis & Contract Manufacturing: A key starting material for custom synthesis houses and CDMOs (Contract Development and Manufacturing Organizations) producing specialized compounds for clients.

Basic Information

Product Name	1H-Pyrrolo[2,3-B]Pyridin-3-Amine, 4,5-Difluoro-
CAS No.	1196507-69-3
Molecular Formula	C7H5F2N3
Molecular Weight	169.13 g/mol
Synonyms	4,5-Difluoro-1H-pyrrolo[2,3-b]pyridin-3-amine; 4,5-Difluoro-3-amino-1H-pyrrolo[2,3-b]pyridine; 4,5-Difluoro-1H-pyrrolo[2,3-b]pyridin-3-ylamine; 3-Amino-4,5-difluoro-1H-pyrrolo[2,3-b]pyridine; 4,5-Difluoro-1H-pyrrolo[2,3-b]pyridin-3-amine (CAS 1196507-69-3); 4,5-Difluoro-3-aminopyrrolo[2,3-b]pyridine
EINECS	Contact for details

Quality Control

Every batch of 1H-Pyrrolo[2,3-B]Pyridin-3-Amine, 4,5-Difluoro- is manufactured under strict quality management systems. Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development use. Comprehensive analytical characterization, including HPLC, NMR, and MS, is performed to confirm identity and purity. Certificates of Analysis (COA) detailing all specifications are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and performance. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.