Description

1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-5-Iodo-1-(Phenylsulfonyl)- is a high-purity, multi-functional heterocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a versatile and reactive scaffold for constructing complex molecular architectures, particularly in pharmaceutical research and development. It is primarily needed by medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of kinase inhibitors and other targeted therapeutic agents.
• Medicinal Chemistry Research: Used extensively in hit-to-lead optimization and structure-activity relationship (SAR) studies due to its modifiable halogen handles.
• Agrochemical Development: Acts as a key building block for creating novel herbicides, fungicides, and insecticides with enhanced efficacy.
• Material Science: Employed in the development of organic electronic materials, such as organic light-emitting diodes (OLEDs) and semiconductors.
• Chemical Biology: Utilized in the design and synthesis of molecular probes and bio-conjugates for studying biological pathways.
• Custom Synthesis & Contract Manufacturing: A valuable starting material for custom synthesis projects requiring complex, functionalized pyrrolopyridine cores.

Basic Information

Item	Details
Product Name	1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-5-Iodo-1-(Phenylsulfonyl)-
CAS No.	1196507-56-8
Molecular Formula	C13H8ClIN2O2S
Molecular Weight	418.63 g/mol
Synonyms	4-Chloro-5-iodo-1-(phenylsulfonyl)-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-5-iodo-1H-pyrrolo[2,3-b]pyridine 1-(Phenylsulfonyl) Derivative; 1-(Benzenesulfonyl)-4-chloro-5-iodo-1H-pyrrolo[2,3-b]pyridine; 4-Chloro-5-iodo-1-tosyl-1H-pyrrolo[2,3-b]pyridine (common alias); 1H-Pyrrolo[2,3-b]pyridine, 4-chloro-5-iodo-1-(phenylsulfonyl)-; 1196507-56-8; 4-Cl-5-I-1-Ps-1H-pyrrolo[2,3-b]pyridine (abbreviated)
EINECS	Contact for details

Quality Control

Our 1H-Pyrrolo[2,3-B]Pyridine, 4-Chloro-5-Iodo-1-(Phenylsulfonyl)- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling should be performed under appropriate conditions to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%
Total Impurities (HPLC)	≤ 3.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.