Description

2-Chloro-6-Ethynylpyrazine is a high-value, multi-functional heterocyclic building block featuring both a halogen and an alkyne functional group. This unique structure makes it a critical intermediate for the synthesis of complex molecules in advanced research and development. It is primarily utilized by pharmaceutical and agrochemical R&D teams for constructing novel active ingredients, as well as by material scientists developing specialty polymers and ligands.

Application

• Pharmaceutical Intermediate: A key synthon for the development of novel drug candidates, particularly in kinase inhibitor and antiviral research programs.
• Agrochemical Synthesis: Used in the construction of advanced active ingredients for crop protection products.
• Material Science: Serves as a building block for creating functionalized polymers, conductive materials, and metal-organic frameworks (MOFs).
• Chemical Biology & Proteomics: Employed in click chemistry applications (e.g., CuAAC reactions) for bioconjugation and probe development.
• Ligand Synthesis: Used to prepare sophisticated pyrazine-based ligands for catalysis and coordination chemistry.
• Academic & Contract Research: A valuable reagent for exploratory synthetic chemistry in academic and industrial R&D laboratories.

Basic Information

Product Name	2-Chloro-6-Ethynylpyrazine
CAS No.	1196157-03-5
Molecular Formula	C6H3ClN2
Molecular Weight	138.56 g/mol
Synonyms	6-Chloro-2-ethynylpyrazine; 2-Ethynyl-6-chloropyrazine; 2-Chloro-6-ethynylpyrazine; Pyrazine, 2-chloro-6-ethynyl-; 1196157-03-5
EINECS	Contact for details

Quality Control

Our 2-Chloro-6-Ethynylpyrazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, GC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry standards for research-grade chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). The compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.